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Tocris Bioscience™ Z-Guggulsterone

Broad spectrum steroid receptor ligand. More active isomer of guggulsterone (Cat. No. 2013)

Brand:  Tocris Bioscience™ 357010

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13463214

  • £183.48 / 10mg


Estimated Shipment
29-11-2018
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Description

Description

Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. More active isomer of guggulsterone (Cat. No. 2013).
Specifications

Specifications

Z-Guggulsterone
>98
10mg
Z-Guggulsterone
312.45
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