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YM 58483, Tocris Bioscience™

Inhibitor of SOCE in non-excitable cells

Brand:  Tocris (Bio-Techne) 393910

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13463844

  • £186.00 / 10mg


Estimated Shipment
21-06-2018
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Description

Description

Blocker of store-operated Ca2+ entry (SOCE), which mediates the activation of non-excitable cells (e.g. lymphocytes). Inhibits calcium release-activated calcium (CRAC) channels; suppresses thapsigargin-induced sustained Ca2+ influx (IC50 = 100 nM). Displays immuno-modulatory and anti-inflammatory effects; suppresses cytokine production and proliferation of T cells in vitro.
Specifications

Chemical Identifiers

YM 58483
C15H9F6N5OS
421.32
N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide

Specifications

YM 58483
>99%
421.32
10mg
223499-30-7
C15H9F6N5OS
N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide
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