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YM 58483, Tocris Bioscience™

Inhibitor of SOCE in non-excitable cells

Brand:  Tocris (Bio-Techne) 393910

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13463844

  • £183.48 / 10mg


Estimated Shipment
22-10-2018
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Description

Description

Blocker of store-operated Ca2+ entry (SOCE), which mediates the activation of non-excitable cells (e.g. lymphocytes). Inhibits calcium release-activated calcium (CRAC) channels; suppresses thapsigargin-induced sustained Ca2+ influx (IC50 = 100 nM). Displays immuno-modulatory and anti-inflammatory effects; suppresses cytokine production and proliferation of T cells in vitro.
Specifications

Chemical Identifiers

223499-30-7
421.321
btp2, crac channel inhibitor, btp2, n-4-3,5-bis trifluoromethyl pyrazol-1-yl phenyl-4-methylthiadiazole-5-carboxamide, n-4-3,5-bis trifluoromethyl-1h-pyrazol-1-yl phenyl-4-methyl-1,2,3-thiadiazole-5-carboxamide, maybridge3_006679, d0jv2p, btp-2, ym hplc, 4-methyl-4'-3,5-bis trifluoromethyl-1h-pyrazol-1-yl-1,2,3-thiadiazole-5-carboxanilide, 1,2,3-thiadiazole-5-carboxamide,n-4-3,5-bis trifluoromethyl-1h-pyrazol-1-yl phenyl-4-methyl
N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
C15H9F6N5OS
XPRZIORDEVHURQ-UHFFFAOYSA-N
2455
CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F

Specifications

YM 58483
223499-30-7
btp2, crac channel inhibitor, btp2, n-4-3,5-bis trifluoromethyl pyrazol-1-yl phenyl-4-methylthiadiazole-5-carboxamide, n-4-3,5-bis trifluoromethyl-1h-pyrazol-1-yl phenyl-4-methyl-1,2,3-thiadiazole-5-carboxamide, maybridge3_006679, d0jv2p, btp-2, ym hplc, 4-methyl-4'-3,5-bis trifluoromethyl-1h-pyrazol-1-yl-1,2,3-thiadiazole-5-carboxanilide, 1,2,3-thiadiazole-5-carboxamide,n-4-3,5-bis trifluoromethyl-1h-pyrazol-1-yl phenyl-4-methyl
CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
421.321
421.32
10mg
C15H9F6N5OS
XPRZIORDEVHURQ-UHFFFAOYSA-N
N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
2455
>99%
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