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YM 511, Tocris Bioscience™

Potent aromatase (CYP19) inhibitor

Brand:  Tocris (Bio-Techne) 327850

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462704

  • £578.52 / 50mg


Estimated Shipment
31-10-2018
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Description

Description

Orally active, potent aromatase (CYP19) inhibitor (IC50 values are 0.4 and 0.12 nM at rat ovary and human placenta cells respectively) that only weakly inhibits the synthesis of other steroid hormones. Reduces plasma estrogen levels into ranges induced by ovariectomy and inhibits testosterone-induced breast cancer cell growth in vitro (IC50 = 0.13 nM).
Specifications

Chemical Identifiers

148869-05-0
354.211
ym511 pharmaceutical, 4-4-bromophenyl methyl-4h-1,2,4-triazol-4-ylamino benzonitrile, benzonitrile,4-4-bromophenyl methyl-4h-1,2,4-triazol-4-ylamino, acmc-20n5jr, d0y2og, 4-4-bromobenzyl 4h-1,2,4-triazol-4-yl amino benzonitrile, 4-4-bromophenyl methyl-1,2,4-triazol-4-yl amino benzonitrile, 4-n-4-bromobenzyl-n-4-cyanophenyl amino-4h-1,2,4-triazole, 4-4-bromophenyl methyl 1,2,4-triazol-4-yl amino benzonitrile, 4-4-bromophenyl methyl 4h-1,2,4-triazol-4-yl amino benzonitrile
4-[(4-bromophenyl)methyl-(1,2,4-triazol-4-yl)amino]benzonitrile
C16H12BrN5
GGPPBTSXFROGAE-UHFFFAOYSA-N
177865
C1=CC(=CC=C1CN(C2=CC=C(C=C2)C#N)N3C=NN=C3)Br

Specifications

YM 511
148869-05-0
ym511 pharmaceutical, 4-4-bromophenyl methyl-4h-1,2,4-triazol-4-ylamino benzonitrile, benzonitrile,4-4-bromophenyl methyl-4h-1,2,4-triazol-4-ylamino, acmc-20n5jr, d0y2og, 4-4-bromobenzyl 4h-1,2,4-triazol-4-yl amino benzonitrile, 4-4-bromophenyl methyl-1,2,4-triazol-4-yl amino benzonitrile, 4-n-4-bromobenzyl-n-4-cyanophenyl amino-4h-1,2,4-triazole, 4-4-bromophenyl methyl 1,2,4-triazol-4-yl amino benzonitrile, 4-4-bromophenyl methyl 4h-1,2,4-triazol-4-yl amino benzonitrile
C1=CC(=CC=C1CN(C2=CC=C(C=C2)C#N)N3C=NN=C3)Br
354.211
354.2
50mg
C16H12BrN5
GGPPBTSXFROGAE-UHFFFAOYSA-N
4-[(4-bromophenyl)methyl-(1,2,4-triazol-4-yl)amino]benzonitrile
177865
>99%
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