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YM 202074, Tocris Bioscience™

High affinity, selective mGlu1 antagonist

Brand:  Tocris (Bio-Techne) 341350

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13442974

  • £727.65 / 50mg

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Description

Description

High affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. Binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. Inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells). Neuroprotective in vivo.
Specifications

Chemical Identifiers

299900-84-8
1177.352
n-cyclohexyl-6-n-2-methoxyethyl-n-methylamino methyl-n-methylthiazolo 3,2-a benzoimidazole-2-carboxamide sesquifumarate
(E)-but-2-enedioic acid;N-cyclohexyl-7-[[2-methoxyethyl(methyl)amino]methyl]-N-methyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide
C56H72N8O16S2
HABHEZNVNBKOQJ-VQYXCCSOSA-N
90488842
CN(CCOC)CC1=CC2=C(C=C1)N=C3N2C=C(S3)C(=O)N(C)C4CCCCC4.CN(CCOC)CC1=CC2=C(C=C1)N=C3N2C=C(S3)C(=O)N(C)C4CCCCC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O

Specifications

50mg
299900-84-8
n-cyclohexyl-6-n-2-methoxyethyl-n-methylamino methyl-n-methylthiazolo 3,2-a benzoimidazole-2-carboxamide sesquifumarate
CN(CCOC)CC1=CC2=C(C=C1)N=C3N2C=C(S3)C(=O)N(C)C4CCCCC4.CN(CCOC)CC1=CC2=C(C=C1)N=C3N2C=C(S3)C(=O)N(C)C4CCCCC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
1177.352
588.67
YM 202074
C56H72N8O16S2
HABHEZNVNBKOQJ-VQYXCCSOSA-N
(E)-but-2-enedioic acid;N-cyclohexyl-7-[[2-methoxyethyl(methyl)amino]methyl]-N-methyl-[1,3]thiazolo[3,2-a]benzimidazole-2-carboxamide
90488842
>99%
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