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Y-27632 dihydrochloride, Tocris Bioscience™

Selective p160ROCK inhibitor

Brand:  RD Systems (Bio-Techne) 1254/1

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 1mg

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Product Code. 13468983

  • £124.95 / 1mg

Estimated Shipment date
from Supplier 25-02-2020

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Description

Description

Selective p160 ROCK inhibitor (Ki values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, PKA and MLCK respectively). Also inhibits PRK2 (IC50 = 600 nM). Smooth muscle relaxant and orally active in vivo. Increases survival rate of human embryonic stem (hES) cells and iPSC-BMECs undergoing cryopreservation. Also optimizes naïve human pluripotent stem cell growth and viability following naïve cell derivation from primed ESCs and iPSCs using naïve human stem cell medium (NHSM).

Y-27632 synthesized to cGMP guidelines also available.

Specifications

Chemical Identifiers

129830-38-2
320.258
y-27632 dihydrochloride, y 27632 dihydrochloride, unii-q9828ii7f3, 1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexanecarboxamide dihydrochloride, 1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride, y 27632 hydrochloride, 4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride, 1r,4r-4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride, r-+-trans-4-1-aminoethyl-n-4-pyridyl cyclohexanecarboxamide dihydrochloride
4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
C14H23Cl2N3O
IDDDVXIUIXWAGJ-DDSAHXNVSA-N
9901617
CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

Specifications

1mg
129830-38-2
y-27632 dihydrochloride, y 27632 dihydrochloride, unii-q9828ii7f3, 1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexanecarboxamide dihydrochloride, 1r,4r-4-r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride, y 27632 hydrochloride, 4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride, 1r,4r-4-1r-1-aminoethyl-n-pyridin-4-yl cyclohexane-1-carboxamide dihydrochloride, r-+-trans-4-1-aminoethyl-n-4-pyridyl cyclohexanecarboxamide dihydrochloride
CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
320.258
320.26
Y-27632 dihydrochloride
C14H23Cl2N3O
IDDDVXIUIXWAGJ-DDSAHXNVSA-N
4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
9901617
>98%
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