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Y-27632 dihydrochloride, Tocris™

Selective p160ROCK inhibitor

Brand:  Tocris (Bio-Techne) 125450

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13488983

  • £900.00 / 50mg


Estimated Shipment
02-11-2017
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Description

Description

Selective p160ROCK inhibitor (Ki values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, PKA and MLCK respectively). Also inhibits PRK2 (IC50 = 600 nM). Smooth muscle relaxant and orally active in vivo. Increases survival rate of human embryonic stem (hES) cells and iPSC-BMECs undergoing cryopreservation. Also optimizes naive human pluripotent stem cell growth and viability following naive cell derivation from primed ESCs and iPSCs using naive human stem cell medium (NHSM).
Specifications

Chemical Identifiers

Y-27632 dihydrochloride
C14H21N3O·2HCl
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
>98%
320.26

Specifications

Y-27632 dihydrochloride
50mg
C14H21N3O·2HCl
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
129830-38-2
>98%
320.26