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Y-27632 dihydrochloride, Tocris Bioscience™

Selective p160ROCK inhibitor

Brand:  Tocris (Bio-Techne) 125450

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13488983

  • £843.48 / 50mg


Estimated Shipment
04-10-2018
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Description

Description

Selective p160ROCK inhibitor (Ki values are 0.14, 26, 25 and > 250 μM for p160ROCK, PKC, PKA and MLCK respectively). Also inhibits PRK2 (IC50 = 600 nM). Smooth muscle relaxant and orally active in vivo. Increases survival rate of human embryonic stem (hES) cells and iPSC-BMECs undergoing cryopreservation. Also optimizes naive human pluripotent stem cell growth and viability following naive cell derivation from primed ESCs and iPSCs using naive human stem cell medium (NHSM).
Specifications

Chemical Identifiers

129830-38-2
320.258
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
C14H23Cl2N3O
IDDDVXIUIXWAGJ-DDSAHXNVSA-N
9901617
CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

Specifications

Y-27632 dihydrochloride
>98%
C14H23Cl2N3O
IDDDVXIUIXWAGJ-DDSAHXNVSA-N
4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
9901617
129830-38-2
50mg
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
320.258
320.26
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