Tocris Bioscience™ Xanomeline oxalate

Functionally selective M1 agonist

Description

Functionally selective muscarinic M1 receptor agonist (EC50 values are 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). Displays a complex pharmacological profile: reversible and wash-resistant binding, resulting in full agonist activity at M1; delayed wash-resistant partial agonist activity at M2; and delayed wash-resistant full agonist activity at M4. Exhibits antipsychotic activity, and improves cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.

Specifications

• Purity: >98%
• Product Type: Xanomeline oxalate
• Molecular Weight (g/mol): 371.46
• Inhibitors: Xanomeline oxalate

For Research Use Only