Tocris Bioscience™ Xanomeline oxalate
Functionally selective M1 agonist
Brand: Tocris Bioscience™ 356950
Code : Z1
Additional Details : Weight : 0.01000kg
DescriptionFunctionally selective muscarinic M1 receptor agonist (EC50 values are 0.3, 5, 42, 52 and 92.5 nM at M1, M3, M5, M4 and M2 receptors respectively). Displays a complex pharmacological profile: reversible and wash-resistant binding, resulting in full agonist activity at M1; delayed wash-resistant partial agonist activity at M2; and delayed wash-resistant full agonist activity at M4. Exhibits antipsychotic activity, and improves cognitive deficits and behavioral disturbances in Alzheimer's disease and schizophrenia.
For Research Use Only