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WR 1065, Tocris Bioscience™

p53 activator. Also ROS scavenger

Brand:  Tocris (Bio-Techne) 335650

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462874

  • £355.74 / 50mg

Estimated Shipment date
from Supplier 25-03-2020

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Description

Description

Cell-permeable reactive oxygen species scavenger that activates p53 through a JNK-dependent signaling pathway. Activates p21waf-1 and MDM2, represses transcription of Myc and thymidine kinase, and inhibits DNA topoisomerase IIα. Induces cell cycle arrest and exhibits cytoprotective activity towards normal cells but not cancer cells in vivo. Also exhibits broad spectrum antiviral activity in vitro.
Specifications

Chemical Identifiers

14653-77-1
207.157
wr 1065 hydrochloride, amifostine thiol dihydrochloride, unii-le9vv16szw, wr-1065 dihydrochloride, 2-3-aminopropyl amino ethanethiol dihydrochloride, 2-3-aminopropylamino ethanethiol dihydrochloride, le9vv16szw, ethanethiol, 2-3-aminopropyl amino-, dihydrochloride, 2-3-aminopropyl amino ethanethiol 2hcl
2-(3-aminopropylamino)ethanethiol;dihydrochloride
C5H16Cl2N2S
XDRLRDHLCIFZIW-UHFFFAOYSA-N
146169
C(CN)CNCCS.Cl.Cl

Specifications

50mg
14653-77-1
wr 1065 hydrochloride, amifostine thiol dihydrochloride, unii-le9vv16szw, wr-1065 dihydrochloride, 2-3-aminopropyl amino ethanethiol dihydrochloride, 2-3-aminopropylamino ethanethiol dihydrochloride, le9vv16szw, ethanethiol, 2-3-aminopropyl amino-, dihydrochloride, 2-3-aminopropyl amino ethanethiol 2hcl
C(CN)CNCCS.Cl.Cl
207.157
207.16
WR 1065
C5H16Cl2N2S
XDRLRDHLCIFZIW-UHFFFAOYSA-N
2-(3-aminopropylamino)ethanethiol;dihydrochloride
146169
>98%
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