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VU 29, Tocris Bioscience™

Potent positive allosteric modulator of mGlu5 receptors

Brand:  RD Systems (Bio-Techne) 4458/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

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Product Code. 13434794

  • £593.88 / 50mg

Estimated Shipment date
from Supplier 20-11-2019

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Description

Description

Potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); binds to the MPEP (Cat. No. 1212) allosteric site (Ki app = 244 nM). Selective for mGlu5 over mGlu1 and mGlu2 receptors (EC50 values are 557 nM and 1.51 μM for mGlu1 and mGlu2 respectively). Potentiates both DHPG-induced LTP and threshold θ-burst stimulation (TBS)-induced LTP in rat hippocampal slices. Analog of CDPPB (Cat. No. 3235).
Specifications

Chemical Identifiers

890764-36-0
384.395
dpap, n-1,3-diphenyl-1h-pyrazol-5-yl-4-nitrobenzamide, 4-nitro-n-1,3-diphenyl-1h-pyrazol-5-yl benzamide, d01qig, d04zbv, n-2,5-diphenylpyrazol-3-yl-4-nitro-benzamide, n-2,5-di phenyl pyrazol-3-yl-4-nitrobenzamide, n-1,3-diphenyl-1h-pyrazolo-5-yl-4-nitrobenzamide, n-2,5-diphenylpyrazol-3-yl-4-nitrobenzamide
N-(2,5-diphenylpyrazol-3-yl)-4-nitrobenzamide
C22H16N4O3
KIALCSMRIHRFPL-UHFFFAOYSA-N
11610682
C1=CC=C(C=C1)C2=NN(C(=C2)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-])C4=CC=CC=C4

Specifications

50mg
890764-36-0
dpap, n-1,3-diphenyl-1h-pyrazol-5-yl-4-nitrobenzamide, 4-nitro-n-1,3-diphenyl-1h-pyrazol-5-yl benzamide, d01qig, d04zbv, n-2,5-diphenylpyrazol-3-yl-4-nitro-benzamide, n-2,5-di phenyl pyrazol-3-yl-4-nitrobenzamide, n-1,3-diphenyl-1h-pyrazolo-5-yl-4-nitrobenzamide, n-2,5-diphenylpyrazol-3-yl-4-nitrobenzamide
C1=CC=C(C=C1)C2=NN(C(=C2)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-])C4=CC=CC=C4
384.395
384.39
VU 29
C22H16N4O3
KIALCSMRIHRFPL-UHFFFAOYSA-N
N-(2,5-diphenylpyrazol-3-yl)-4-nitrobenzamide
11610682
>99%
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