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VU 0364770, Tocris Bioscience™

Positive allosteric modulator at mGlu4

Brand:  RD Systems (Bio-Techne) 4469/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13444804

  • £124.20 / 10mg

Estimated Shipment
28-06-2019

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Description

Description

Positive allosteric modulator at mGlu4 receptors (EC50 = 290 nM in mGlu4-expressing HEK 293 cells). Reverses haloperidol-induced catalepsy in rats; prevents attentional deficit and forelimb asymmetry in a rodent model of Parkinson's disease. Exhibits affinity for MAO-B and MAO-A (Ki values are 0.72 μM and 8.5 μM respectively). Brain penetrant.
Specifications

Chemical Identifiers

61350-00-3
232.667
n-3-chlorophenyl picolinamide, n-3-chlorophenyl-2-pyridinecarboxamide, n-3-chlorophenyl pyridine-2-carboxamide, 2-pyridinecarboxamide, n-3-chlorophenyl, d0w9vn, n-3-chloro-phenyl-pyridine-2-carboxamide
N-(3-chlorophenyl)pyridine-2-carboxamide
C12H9ClN2O
SUYUTNCKIOLMAJ-UHFFFAOYSA-N
836002
C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl

Specifications

VU 0364770
61350-00-3
n-3-chlorophenyl picolinamide, n-3-chlorophenyl-2-pyridinecarboxamide, n-3-chlorophenyl pyridine-2-carboxamide, 2-pyridinecarboxamide, n-3-chlorophenyl, d0w9vn, n-3-chloro-phenyl-pyridine-2-carboxamide
C1=CC=NC(=C1)C(=O)NC2=CC(=CC=C2)Cl
232.667
232.67
10mg
C12H9ClN2O
SUYUTNCKIOLMAJ-UHFFFAOYSA-N
N-(3-chlorophenyl)pyridine-2-carboxamide
836002
>99%
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