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Vinorelbine ditartrate, Tocris Bioscience™

Selective mitotic microtubule antagonist

Brand:  Tocris (Bio-Techne) 340150

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462954

  • £506.00 / 50mg


Estimated Shipment
31-08-2018
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Description

Description

Selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. Inhibits proliferation of multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells) and blocks metaphase/anaphase transition by suppression of microtubule dynamics (IC50 = 3.8 nM). Reduces spindle length by 29% and inhibits microtubule polymerization at micromolar concentrations.
Specifications

Chemical Identifiers

125317-39-7
1079.119
(2β,3β,4β,5α,12R,19α)-4-(Acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy
C53H66N4O20
CILBMBUYJCWATM-HJBYVSOESA-N
124080885

Specifications

Vinorelbine ditartrate
>98%
(2β,3β,4β,5α,12R,19α)-4-(Acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy
CCC1=CC2CC(C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O.C(C(C(=O)O)O)(C(=O)O)O
124080885
1079.1
125317-39-7
C53H66N4O20
CILBMBUYJCWATM-HJBYVSOESA-N
1079.119
50mg
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