vinculin Mouse, Alexa Fluor 488, Clone: 7F9, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9777-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15550297

Quantity Price
1 £ 73.93 / 25µg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 25μg
Clone 7F9
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Regulatory Status RUO
Isotype IgG1
Format Conjugated
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Antigen vinculin
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Alexa Fluor 488
Species Reactivity Human, Mouse, Rat
Host Species Mouse

The monoclonal antibody 7F9 (VIIF9) recognizes human, mouse, rat, and avian vinculin and its alternatively spliced isoform, metavinculin. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Vinculin is involved in the anchoring of F-actin to the membrane and the regulation of E-cadherin expression. Vinculin binds to talin, paxillin, and alpha-actinin. Disregulation of vinculin alters cell adhesion, migration, and growth, which promotes cancer invasion and metastasis.