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VER 155008, Tocris Bioscience™

Hsp70 inhibitor

Brand:  Tocris (Bio-Techne) 380310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13463624

  • £183.48 / 10mg


Estimated Shipment
02-01-2019
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Description

Description

Novel adenosine-derived inhibitor of Heat Shock Protein 70 (Hsp70) (IC50 = 0.5μM). Inhibits cell proliferation of multiple human tumor cell lines in vitro. Also binds Hsc70 and Grp78; displays selectivity against Hsp90β (IC50 >200μM for Hsp90β).
Specifications

Chemical Identifiers

1134156-31-2
556.404
5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl methyl amino-adenosine, 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl-methyl amino-adenosine, 4-2r,3s,4r,5r-5-6-amino-8-3,4-dichlorobenzyl amino-9h-purin-9-yl-3,4-dihydroxytetrahydrofuran-2-yl methoxy methyl benzonitrile, 3fd, d0h0au, adenosine-derived inhibitor, 12, hsp 70 inhibitor cancer , vernalis, adenosine-derived inhibitor grp78 , 13, ver hplc, heat shock protein 70 inhibitor cancer , vernalis
4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile
C25H23Cl2N7O4
ZXGGCBQORXDVTE-UMCMBGNQSA-N
25195348
C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N

Specifications

VER 155008
1134156-31-2
5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl methyl amino-adenosine, 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl-methyl amino-adenosine, 4-2r,3s,4r,5r-5-6-amino-8-3,4-dichlorobenzyl amino-9h-purin-9-yl-3,4-dihydroxytetrahydrofuran-2-yl methoxy methyl benzonitrile, 3fd, d0h0au, adenosine-derived inhibitor, 12, hsp 70 inhibitor cancer , vernalis, adenosine-derived inhibitor grp78 , 13, ver hplc, heat shock protein 70 inhibitor cancer , vernalis
C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N
556.404
556.4
10mg
C25H23Cl2N7O4
ZXGGCBQORXDVTE-UMCMBGNQSA-N
4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethyl]benzonitrile
25195348
>98%
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