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VEGF Receptor 3 Rat anti-Mouse, Biotin, Clone: AFL4, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-5988-85

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15229989

  • £176.70 / 500µg


Estimated Shipment date
from Supplier 26-09-2017
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Disclaimers:

For Research Use Only.


Description

Description

The AFL4 monoclonal antibody reacts with the mouse VEGF receptor-3, also known as Flt-4. This 195kDa molecule was identified as an endothelial-specific member of the receptor tyrosine kinase (RTK) family. During early embryogenesis all endothelial cells express VEGFR-3, while in the adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. However, VEGFR-3 expression is induced in the adult tissue upon tumor implementation suggesting an important role for this receptor in the tumor angiogenesis. VEGF-C and VEGF-D bind to and activate VEGFR-3. AFL4 is an antagonist mAb.
Specifications

Specifications

VEGF Receptor 3
AFL4
Biotin
Conjugated
Rat
500μg
Store at 2-8°C. Do not freeze.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
VEGFR3, VEGF R3, VEGF receptor 3, Flt-4, Flt4, vascular endothelial growth factor receptor 3
IgG2a
RUO
Primary
Murine