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Varenicline tartrate, Tocris Bioscience™

Selective α4β2 partial agonist; orally active

Brand:  Tocris (Bio-Techne) 375410

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13443554

  • £196.68 / 10mg

Estimated Shipment
09-07-2019

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Description

Description

Orally active, subtype-selective partial agonist at α4β2 nicotinic receptors (Ki values are 0.06, 240, 322 and 3540 nM for α4β2, α3β4, α7, α1βγδ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo. Also potently activates PSAM4-5-HT3 and PSAM4-GlyR chimeric ion channels (EC50 values are 4 and 1.6 nM, respectively)
Specifications

Chemical Identifiers

375815-87-5
361.354
varenicline tartrate
C1C2CNCC1C3=CC4=NC=CN=C4C=C23.C(C(C(=O)O)O)(C(=O)O)O
C17H19N3O6
TWYFGYXQSYOKLK-ZBABXEQTSA-N
124080896

Specifications

Varenicline tartrate
375815-87-5
varenicline tartrate
C1C2CNCC1C3=CC4=NC=CN=C4C=C23.C(C(C(=O)O)O)(C(=O)O)O
124080896
>99%
10mg
C17H19N3O6
TWYFGYXQSYOKLK-ZBABXEQTSA-N
361.354
361.37
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