V beta 6 TCR Rat anti-Mouse, APC, Clone: RR4-7, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-5795-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15390750

Quantity Price
1 £ 60.53 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Conjugate Allophycocyanin
Clone RR4-7
Primary or Secondary Primary
Gene Alias Vb6-TCR, Vb-6
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Concentration 0.2mg/mL
Species Reactivity Mouse
Isotype IgG2b
Quantity 25μg
Antigen V beta 6 TCR
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Applications Flow Cytometry
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

This RR4-7 monoclonal antibody reacts with mouse V beta 6 TCR. Composed of an a and b chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement. The RR4-7 antibody recognizes the V beta 6 chain on T cells from mouse strains with the a (e.g., C57BR and SJL) and b haplotypes (e.g., BALB/c, C3H, and DBA/1). Reports indicate that strains expressing the Mls-1a antigen, particularly in the presence of MHC Class II I-E, possess fewer V beta 6 TCR+ T cells.

The RR4-7 antibody has been reported to have functional activity in vitro and in vivo.