V beta 5.1 TCR Mouse anti-Human, PE-Cy7, Clone: LC4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-5832-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15558576

Quantity Price
1 £ 72.77 / 25 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Antigen V beta 5.1 TCR
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Quantity 25 tests
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG1
Format Conjugated
Conjugate PE-Cy7
Host Species Mouse
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Clone LC4
Applications Flow Cytometry
Primary or Secondary Primary
Concentration 5μL (0.25μg)/test

This LC4 monoclonal antibody recognizes the human T cell receptor (TCR) Vβ5.1 allele. Composed of an α and β chain, TCR specificity is typically determined by Vα, Jα, Vβ, Dβ, and Jβ gene rearrangement. Vβ expression in humans has been examined in studies on the effects of superantigens, inflammation, autoimmune disease, and HIV infection. More recently, assessment of TCR Vβ expression has been used to phenotype T cell clonality in CD3+/TCRαβ+ large granular lymphocyte leukemias. A member of the Ig superfamily, this receptor is expressed on a subset of peripheral blood T cells.

This monoclonal antibody has been reported to induce apoptosis and calcium flux.