V beta 5.1 TCR Mouse anti-Human, APC, Clone: LC4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-5832-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15598136

Quantity Price
1 £ 182.82 / 100 tests
EU Stock 3
Add to basket


Description and Specification

Specification

Conjugate APC
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Primary or Secondary Primary
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Antigen V beta 5.1 TCR
Quantity 100 tests
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 5μL (0.5μg)/test
Isotype IgG1
Clone LC4
Host Species Mouse
Applications Flow Cytometry
Format Conjugated

This LC4 monoclonal antibody recognizes the human T cell receptor (TCR) Vβ5.1 allele. Composed of an α and β chain, TCR specificity is typically determined by Vα, Jα, Vβ, Dβ, and Jβ gene rearrangement. Vβ expression in humans has been examined in studies on the effects of superantigens, inflammation, autoimmune disease, and HIV infection. More recently, assessment of TCR Vβ expression has been used to phenotype T cell clonality in CD3+/TCRαβ+ large granular lymphocyte leukemias. A member of the Ig superfamily, this receptor is expressed on a subset of peripheral blood T cells.

This monoclonal antibody has been reported to induce apoptosis and calcium flux.