V beta 5.1 TCR Mouse anti-Human, APC, Clone: LC4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-5832-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15588136

Quantity Price
1 £ 72.77 / 25 tests
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Applications Flow Cytometry
Isotype IgG1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate APC
Monoclonal or Polyclonal Monoclonal
Species Reactivity Human
Primary or Secondary Primary
Host Species Mouse
Quantity 25 tests
Concentration 5μL (0.5μg)/test
Antigen V beta 5.1 TCR
Clone LC4
Format Conjugated
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.

This LC4 monoclonal antibody recognizes the human T cell receptor (TCR) Vβ5.1 allele. Composed of an α and β chain, TCR specificity is typically determined by Vα, Jα, Vβ, Dβ, and Jβ gene rearrangement. Vβ expression in humans has been examined in studies on the effects of superantigens, inflammation, autoimmune disease, and HIV infection. More recently, assessment of TCR Vβ expression has been used to phenotype T cell clonality in CD3+/TCRαβ+ large granular lymphocyte leukemias. A member of the Ig superfamily, this receptor is expressed on a subset of peripheral blood T cells.

This monoclonal antibody has been reported to induce apoptosis and calcium flux.