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TCR V beta 5.1, APC, clone: LC4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-5832-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15588136

  • £74.99 / 25 tests


Estimated Shipment date
from Supplier 28-02-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: This LC4 monoclonal antibody recognizes the human T cell receptor (TCR) Vbeta5.1 allele. Composed of an alpha and beta chain, TCR specificity is typically determined by Valpha, Jalpha, Vbeta, Dbeta, and Jbeta gene rearrangement. Vbeta expression in humans has been examined in studies on the effects of superantigens, inflammation, autoimmune disease, and HIV infection. More recently, assessment of TCR Vbeta expression has been used to phenotype T cell clonality in CD3+/TCRalpha beta+ large granular lymphocyte leukemias. A member of the Ig superfamily, this receptor is expressed on a subset of peripheral blood T cells.This monoclonal antibody has been reported to induce apoptosis and calcium flux.Applications Reported: This LC4 antibody has been reported for use in flow cytometric analysis.Applications Tested: This LC4 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

V beta 5.1 TCR
LC4
APC
Conjugated
IgG1
RUO
Primary
Human
Flow Cytometry
5μL (0.5μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
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