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V beta 11 TCR Rat anti-Mouse, APC, Clone: RR3-15, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-5827-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15548136

  • £72.77 / 25µg


Estimated Shipment date
from Supplier 30-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This RR3-15 monoclonal antibody reacts with the mouse T-cell receptor (TCR) V beta 11 chain. Composed of an alpha and beta chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement. The RR3-15 antibody recognizes the V beta 11 chain on T cells from mouse strains with the b haplotype in the Tcrb gene complex, including C57BL/6 and B10, but is absent in mice with the a haplotype, such as C57L, SJL, and SWR. In addition, reports indicate that Vbeta11+ T cells are eliminated in mice bearing the MHC Class II I-E molecule. Finally, V beta 11+CD4+ T cells have been associated with graft-versus-host disease (GVHD) severity.

The RR3-15 antibody has been reported to activate V beta 11+ T cells.
Description & Specifications

Specifications

V beta 11 TCR
RR3-15
Allophycocyanin
Conjugated
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Vb11, Vbeta11
IgG2b
RUO
Primary
Murine