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UCL 2077, Tocris Bioscience™

Slow afterhyperpolarization (sAHP) channel blocker; sub-type selective Kv channel effects

Brand:  Tocris (Bio-Techne) 266110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13461674

  • £141.75 / 10mg


Estimated Shipment
29-11-2018
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Description

Description

Slow afterhyperpolarization (sAHP) channel blocker; reduces sAHP in hippocampal slice preparations. Displays no effect on Ca2+ currents or the time course of sAHP/sIAHP. Exhibits potent inhibition of KCNQ1 and KCNQ2, but differential effects at other KCNQs. Rescues memory retrieval in dopamine β-hydroxylase knockout mice.
Specifications

Chemical Identifiers

918311-87-2
350.465
3-triphenylmethylaminomethyl pyridine, pyridin-3-ylmethyl triphenylmethyl amine, n-trityl-3-pyridinemethanamine, 3-tribenzylaminomethyl pyridine, ucl hplc , solid, 1,1,1-triphenyl-n-pyridin-3-yl methyl methanamine
1,1,1-triphenyl-N-(pyridin-3-ylmethyl)methanamine
C25H22N2
PQFNWDHABGBCHB-UHFFFAOYSA-N
24868317
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCC4=CN=CC=C4

Specifications

UCL 2077
918311-87-2
3-triphenylmethylaminomethyl pyridine, pyridin-3-ylmethyl triphenylmethyl amine, n-trityl-3-pyridinemethanamine, 3-tribenzylaminomethyl pyridine, ucl hplc , solid, 1,1,1-triphenyl-n-pyridin-3-yl methyl methanamine
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCC4=CN=CC=C4
350.465
350.46
10mg
C25H22N2
PQFNWDHABGBCHB-UHFFFAOYSA-N
1,1,1-triphenyl-N-(pyridin-3-ylmethyl)methanamine
24868317
>99%
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