missing translation for 'onlineSavingsMsg'
Learn More

Tocris Bioscience™ UBP 310

GluK1-selective kainate antagonist

POA

Specifications

Purity >98%
View More Specs

Description

Description

GluK1 (formerly GLUK5) kainate receptor antagonist (IC50 = 130 nM); also blocks recombinant homomeric GluK3 (forrmerly GLUK7) receptors. Displays 12,700-fold selectivity for GluK1 (formerly GLUK5) over GluK2 (formerly GLUK6). Exhibits no activity at mGlu group I or NMDA receptors at concentrations of up to 10 μM. Apparent KD value is 18 ± 4 nM for depression of kainate responses on the dorsal root.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Specifications

>98%
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only