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UBP 302, Tocris Bioscience™

Potent and selective kainate antagonist; active enantiomer of UBP 296 (Cat. No. 2078)

Brand:  Tocris (Bio-Techne) 2079/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13460434

  • £231.01 / 10mg


Estimated Shipment
31-08-2018
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Description

Description

Potent and selective GLUK5 (GluR5)-subunit containing kainate receptor antagonist (apparent KD = 402 nM); active enantiomer of UBP 296 (Cat. No. 2078). Displays ∽ 260-fold selectivity over AMPA receptors, ∽ 90-fold selectivity over recombinant human GLUK6- and GLUK2-containing kainate receptors and has little or no action at NMDA or group I mGlu receptors. Selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibers. Also protects against soman-induced seizures and neuronal degeneration for up to 30 days when administered one hour after soman exposure.
Specifications

Chemical Identifiers

745055-91-8
333.3
(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2, 4-dione
C15H15N3O6
UUIYULWYHDSXHL-NSHDSACASA-N
6420161

Specifications

UBP 302
10mg
C15H15N3O6
UUIYULWYHDSXHL-NSHDSACASA-N
2-[[3-[(2S)-2-amino-2-carboxyethyl]-2,6-dioxopyrimidin-1-yl]methyl]benzoic acid
6420161
745055-91-8
>98%
(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2, 4-dione
C1=CC=C(C(=C1)CN2C(=O)C=CN(C2=O)CC(C(=O)O)N)C(=O)O
333.3
333.3
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