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U 73122, Tocris Bioscience™

Phospholipase C inhibitor

Brand:  Tocris (Bio-Techne) 1268/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13459023

  • £133.65 / 10mg


Estimated Shipment
31-10-2018
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Description

Description

Phospholipase C inhibitor. Inhibits agonist-induced platelet aggregation with IC50 values of 1-5 μM. Potently inhibits human polymorphonuclear neutrophil adhesion on biological surfaces (IC50 < 50 nM) and exhibits antinociceptive activity in vivo. Also activates TRPM4 and inhibits TRPM3 channels. Negative control U 73343 (Cat. No. 4133) also available.
Specifications

Chemical Identifiers

112648-68-7
464.65
1-6-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1h-pyrrole-2,5-dione, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-17-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, d04por, 1-6-17beta-3-methoxyestra-1 10 ,2,4-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl pyrrole-2,5-dione, 1-6-17?-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-8r,9s,13s,14s,17s-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta a phenanthren-17-yl amino hexyl-1h-pyrrole-2,5-dione
1-[6-[[(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione
C29H40N2O3
LUFAORPFSVMJIW-ZRJUGLEFSA-N
104794
CC12CCC3C(C1CCC2NCCCCCCN4C(=O)C=CC4=O)CCC5=C3C=CC(=C5)OC

Specifications

U 73122
112648-68-7
1-6-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1h-pyrrole-2,5-dione, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-17-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, d04por, 1-6-17beta-3-methoxyestra-1 10 ,2,4-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-17beta-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl pyrrole-2,5-dione, 1-6-17?-3-methoxyestra-1,3,5 10-trien-17-yl amino hexyl-1h-pyrrole-2,5-dione, 1-6-8r,9s,13s,14s,17s-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6h-cyclopenta a phenanthren-17-yl amino hexyl-1h-pyrrole-2,5-dione
CC12CCC3C(C1CCC2NCCCCCCN4C(=O)C=CC4=O)CCC5=C3C=CC(=C5)OC
464.65
464.65
10mg
C29H40N2O3
LUFAORPFSVMJIW-ZRJUGLEFSA-N
1-[6-[[(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione
104794
>98%
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