missing translation for 'onlineSavingsMsg'
Learn More

Alfa Aesar™ Tyrphostin A23, 99%

Potent inhibitor of EGF receptor kinase activity

Brand:  Alfa Aesar™ J60308.MB

Code : NEW

Additional Details : CAS Number : 118409-57-7 Weight : 0.00025kg

Quantity 25mg

 View more versions of this product

Product Code. 15403109

  • £213.00 / 25mg

Estimated Shipment: 27-08-2021

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Applications
Tyrphostin inhibit protein tyrosine kinase and block the EGF-dependent autophosphorylation of the receptor. The inhibitors can bind to the EGF receptor kinase domain with different affinities. It also inhibits PDGFR kinase. Tyrphostin A23 has been used to inhibit agonist-induced GP IIb- IIIa activation in permeabilized platelets and in other studies to block calcium channel currents in vascular smooth muscle cells. . Tyrphostin A23 can also inhibit the internalization of (125)I-transferrin in Heb7a cells.

Solubility
Soluble in DMSO, ethanol, or DMF

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, acids, heat.
Specifications

Chemical Identifiers

118409-57-7
186.17
VTJXFTPMFYAJJU-UHFFFAOYSA-N
2052
C1=CC(=C(C=C1C=C(C#N)C#N)O)O
C10H6N2O2
MFCD00133899
tyrphostin 23, tyrphostin a23, 3,4-dihydroxybenzylidene malononitrile, tyrphostin ag18, tyrphostin rg50810, unii-rv0gcd31oj, 2-3,4-dihydroxyphenyl methylidene propanedinitrile, 2-3,4-dihydroxybenzylidene malononitrile, alpha-cyano-3,4-dihydroxy cinnamonitrile, propanedinitrile,2-3,4-dihydroxyphenyl methylene
2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile

Specifications

Tyrphostin A23
25mg
C10H6N2O2
tyrphostin 23, tyrphostin a23, 3,4-dihydroxybenzylidene malononitrile, tyrphostin ag18, tyrphostin rg50810, unii-rv0gcd31oj, 2-3,4-dihydroxyphenyl methylidene propanedinitrile, 2-3,4-dihydroxybenzylidene malononitrile, alpha-cyano-3,4-dihydroxy cinnamonitrile, propanedinitrile,2-3,4-dihydroxyphenyl methylene
VTJXFTPMFYAJJU-UHFFFAOYSA-N
2-[(3,4-dihydroxyphenyl)methylidene]propanedinitrile
2052
Powder
Brown to Yellow
118409-57-7
MFCD00133899
Soluble in DMSO, ethanol, or DMF
C1=CC(=C(C=C1C=C(C#N)C#N)O)O
186.17
186.17
99%
Videos
SDS Documents
Certificates