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Troglitazone, Tocris Bioscience™

Selective PPARγ agonist; antidiabetic agent

Brand:  Tocris (Bio-Techne) 311450

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462464

  • £435.52 / 50mg


Estimated Shipment
31-08-2018
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Description

Description

Selective PPARγ receptor agonist (EC50 values are 780 and 555 nM at murine and human PPARγ receptors respectively). Displays no activity at PPARα or PPARδ receptors. Antidiabetic agent; exerts potent glucose-lowering effects in insulin-resistant diabetic mice. Displays anti-invasive effect on human breast cancer cells; reduces migration, adhesion and spreading on fibronectin-coated plates. Also inhibits cell growth of hematopoietic cell lines. Inhibits lamellipodia formation and actin polymerization.
Specifications

Chemical Identifiers

97322-87-7
441.542
5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione
CHEBI:9753
C24H27NO5S
GXPHKUHSUJUWKP-UHFFFAOYSA-N
5591

Specifications

Troglitazone
>97%
5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione
CC1=C(C(=C2CCC(OC2=C1C)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C)O
441.542
CHEBI:9753
50mg
97322-87-7
C24H27NO5S
GXPHKUHSUJUWKP-UHFFFAOYSA-N
5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5591
441.54
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