Trifluoromethanesulfonic anhydride, 98%, Thermo Scientific Chemicals

Description

Alfa Aesar Trifluoromethanesulfonic anhydride, 98%, Quantity: 250g, Boiling Point: 81 deg.C to 83 deg.C, Melting Point: -80 deg.C, Molecular Weight: 282.127, Percent Purity: 98%, Beilstein: 1813600, CAS: 358-23-6, ChEBI: CHEBI:48509, Density: 1.72

Trifluoromethanesulfonic anhydride is used to convert phenols and imine into triflic ester and NTf group. It is a strong electrophile used for the introduction of triflyl group in chemical synthesis. It serves as a reagent in the preparation of alkyl and vinyl triflates, and for the stereoselective synthesis of mannosazide methyl uronate donors. It acts as a catalyst for glycosylation with anomeric hydroxy sugars to prepare polysaccharides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trifluoromethanesulfonic anhydride is used to convert phenols and imine into triflic ester and NTf group. It is a strong electrophile used for the introduction of triflyl group in chemical synthesis. It serves as a reagent in the preparation of alkyl and vinyl triflates, and for the stereoselective synthesis of mannosazide methyl uronate donors. It acts as a catalyst for glycosylation with anomeric hydroxy sugars to prepare polysaccharides.

Solubility
Miscible with dichloromethane. Immiscible with hydrocarbons.

Notes
Moisture sensitive. Incompatible with water, strong bases, strong oxidizing agents, acids and alcohols.

Specifications

• Melting Point: -80°C
• Density: 1.72
• Boiling Point: 81°C to 83°C
• Linear Formula: (CF₃SO₂)₂O
• Refractive Index: 1.321
• Quantity: 10 g
• UN Number: UN3265
• Beilstein: 1813600
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with dichloromethane. Immiscible with hydrocarbons.
• Formula Weight: 282.13
• Percent Purity: 98%
• Chemical Name or Material: Trifluoromethanesulfonic anhydride

Safety and Handling

Product Identifier

• Trifluoromethanesulfonic anhydride

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 1
• Substances and mixtures corrosive to metals Category 1
• Skin corrosion/irritation Category 1 A

Hazard Statement

• H290-May be corrosive to metals.
• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : trifluoro-Methanesulfonic acid anhydride

RUO – Research Use Only