Trifluoroacetic Acid, Optima™ LC/MS Grade, Fisher Chemical™

Product Code	Brand	Quantity	Packaging
10155347	Fisher Chemical A116-05AMP	0.5mL	Ampule
10266617	Fisher Chemical A116-1AMP	1mL	Ampule
10378747	Fisher Chemical A116-2AMP	2mL	Ampule
10125637	Fisher Chemical A116-10X1AMP	10mL	Ampules
10723857	Fisher Chemical A116-50	50mL	Amber Glass

Description

Trifluoroacetic Acid, >-99.5%, C2HF3O2, CAS Number-76-05-1, trifluoroethanoic acid, trifluoroacetic acid, cf3cooh, acetic acid, trifluoro, trifluoro-acetic acid, perfluoroacetic acid, kyselina trifluoroctova, trifluoro acetic acid, trifluoracetic acid, trifluoroaceticacid, 50mL

• Ideal high purity mobile phase additive for LC/MS and UHPLC-UV applications
• Evaluated for metal impurities at ppb concentrations for minimal metal mass adduct formation
• Screened for UV-absorbing contaminants to reduce interferences and for smoother baselines
• TFA is a common mobile phase additive that can function as an ion pair reagent

Chemical Identifiers

• CAS: 76-05-1
• Molecular Weight (g/mol): 114.023
• InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N
• PubChem CID: 6422
• IUPAC Name: 2,2,2-trifluoroacetic acid

• Molecular Formula: C2HF3O2
• MDL Number: 4169
• Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
• ChEBI: CHEBI:45892
• SMILES: C(=O)(C(F)(F)F)O

Specifications

• Absorbance: 0.003 AU max. at 254nm, 0.03 AU max. at 300nm, 0.06 AU max. at 230nm, 0.06 AU max. at 275nm, 0.18 AU max. at 220nm, 0.55 AU max. at 210nm
• CAS: 76-05-1
• Aluminum (Al): 20 ppb max.
• Calcium (Ca): 50 ppb max.
• Linear Formula: CF₃COOH
• MDL Number: 4169
• Synonym: trifluoroacetic acid, perfluoroacetic acid, trifluoroethanoic acid, trifluoracetic acid, acetic acid, trifluoro, trifluoroaceticacid, cf3cooh, trifluoro acetic acid, trifluoro-acetic acid, kyselina trifluoroctova
• InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N
• SMILES: C(=O)(C(F)(F)F)O
• Molecular Weight (g/mol): 114.023
• ChEBI: CHEBI:45892
• Physical Form: Liquid
• Grade: OPTIMA™ LC-MS
• Identification: Pass Test
• Lead (Pb): 10 ppb max.
• Manganese (Mn): 10 ppb max.
• Nickel (Ni): 10 ppb max.
• Potassium (K): 20 ppb max.
• Silver (Ag): 10 ppb max.
• Sulfate: Report ppm
• Water: 0.05% max.
• Vapor Density: 3.9
• pH: 0.45
• Boiling Point: 72°C

• Chemical Name or Material: Trifluoroacetic Acid
• Additional Information: Vapor Pressure: 107mbar at 25°C; Vapor Density: 3.9
• Assay Percent Range: ≥99.5 %
• Molecular Formula: C2HF3O2
• Chloride: Report ppm
• Merck Index: 15, 9847
• Density: 1.535g/cm³
• Copper (Cu): 10 ppb max.
• IUPAC Name: 2,2,2-trifluoroacetic acid
• PubChem CID: 6422
• Formula Weight: 114.02
• Percent Purity: ≥99.5%
• Fluoride: Report ppm
• Iron (Fe): 10 ppb max.
• LCMS Gradient Suitability: Pass Test
• Magnesium (Mg): 10 ppb max.
• Packaging: Ampule
• Residue after Evaporation: 1ppm max.
• Sodium (Na): 50 ppb max.
• Vapor Pressure: 107mbar 25
• Zinc (Zn): 20 ppb max.
• Melting Point: -15°C
• Color: Colorless
• Quantity: 0.5mL

Safety and Handling

Product Identifier

• TRIFLUOROACETIC ACID

Signal Word

• Danger

Hazard Category

• Substances and mixtures corrosive to metals Category 1
• Acute toxicity Category 4
• Skin corrosion/irritation Category 1 A
• Serious eye damage/eye irritation Category 1
• LONG-TERM AQUATIC HAZARD Chronic 3

Hazard Statement

• H290-May be corrosive to metals.
• H332-Harmful if inhaled.
• H314-Causes severe skin burns and eye damage.
• H412-Harmful to aquatic life with long lasting effects.

Precautionary Statement

• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.