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Trefoil Factor 3 Mouse anti-Mouse, Rat, eFluor 660, Clone: 5UCLNT3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-4758-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15569946

  • £164.47 / 100µg


Estimated Shipment date
from Supplier 04-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody 5UCLNT3 recognizes mouse and rat Trefoil Factor 3. Trefoil Factor 3 (TFF3) is a member of the trefoil family, which are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF3 is a small peptide hormone secreted by mucus-producing cells and by epithelial cells of multiple tissues, including the gastrointestinal tract, kidney, and breast. TFF3 plays an essential role in both mucosal surface maintenance and restitution. TFF3 facilitates restoration of the intestinal epithelium as a protective barrier against injury by inhibiting apoptosis and promoting survival and migration of epithelial cells. TFF3 also plays a role in inducing airway epithelial ciliated cell differentiation. Levels of TFF3 change after renal injury and urinary levels can be used as a biomarker for kidney tubular injury. TFF3 may also play a role in breast tumor progression and tumor cell dissemination.
Description & Specifications

Specifications

Trefoil Factor 3
5UCLNT3
eFluor 660
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Microscopy
0.2mg/mL
Conjugated
TFF3
IgG1
RUO
Primary
Rat