Trefoil Factor 3 Mouse anti-Mouse, Rat, eFluor 660, Clone: 5UCLNT3, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-4758-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg

Disclaimers: For Research Use Only.

Product Code. 15569946

Quantity Price
1 £ 164.47 / 100µg
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification


Antigen Trefoil Factor 3
Primary or Secondary Primary
Quantity 100μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Concentration 0.2mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Host Species Mouse
Species Reactivity Mouse, Rat
Gene Alias TFF3
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Conjugate eFluor 660
Isotype IgG1
Clone 5UCLNT3

The monoclonal antibody 5UCLNT3 recognizes mouse and rat Trefoil Factor 3. Trefoil Factor 3 (TFF3) is a member of the trefoil family, which are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF3 is a small peptide hormone secreted by mucus-producing cells and by epithelial cells of multiple tissues, including the gastrointestinal tract, kidney, and breast. TFF3 plays an essential role in both mucosal surface maintenance and restitution. TFF3 facilitates restoration of the intestinal epithelium as a protective barrier against injury by inhibiting apoptosis and promoting survival and migration of epithelial cells. TFF3 also plays a role in inducing airway epithelial ciliated cell differentiation. Levels of TFF3 change after renal injury and urinary levels can be used as a biomarker for kidney tubular injury. TFF3 may also play a role in breast tumor progression and tumor cell dissemination.