Trefoil Factor 3 Mouse anti-Mouse, Rat, Clone: 5UCLNT3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-4758-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15557446

Quantity Price
1 £ 142.93 / 100µg
Estimated Shipment date
from Supplier 10-05-2017
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Description and Specification

Specification

Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Applications Western Blotting
Conjugate Unlabeled
Gene Alias TFF3
Isotype IgG1
Antigen Trefoil Factor 3
Species Reactivity Mouse, Rat
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Storage Requirements Store at 2-8°C.
Clone 5UCLNT3
Concentration 0.5mg/mL
Format Purified
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Regulatory Status RUO
Quantity 100μg
Primary or Secondary Primary

The monoclonal antibody 5UCLNT3 recognizes mouse and rat Trefoil Factor 3. Trefoil Factor 3 (TFF3) is a member of the trefoil family, which are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF3 is a small peptide hormone secreted by mucus-producing cells and by epithelial cells of multiple tissues, including the gastrointestinal tract, kidney, and breast. TFF3 plays an essential role in both mucosal surface maintenance and restitution. TFF3 facilitates restoration of the intestinal epithelium as a protective barrier against injury by inhibiting apoptosis and promoting survival and migration of epithelial cells. TFF3 also plays a role in inducing airway epithelial ciliated cell differentiation. Levels of TFF3 change after renal injury and urinary levels can be used as a biomarker for kidney tubular injury. TFF3 may also play a role in breast tumor progression and tumor cell dissemination.