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Trap 101, Tocris Bioscience™

Potent and selective NOP antagonist; active in vivo

Brand:  Tocris (Bio-Techne) 250850

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13461364

  • £700.00 / 50mg


Estimated Shipment
31-08-2018
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Description

Description

Potent and selective nociceptin/orphanin FQ (NOP) receptor antagonist (pA2 = 7.75). Displays selectivity for NOP receptors over classical opioid receptors (pKi values are 8.65, 6.60, 6.14 and < 5 for NOP,μ-, κ-, and δ-opioid receptors respectively). Attenuates motor deficits in a rat model of Parkinson's Disease. Active in vivo.
Specifications

Chemical Identifiers

1216621-00-9
434.021
1-[1-(Cyclooctylmethyl)-1,2,3,6-tetrahydro-5-(hydroxymethyl)-4-pyridinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one hydrochloride
C24H36ClN3O2
YEVMLMQAMCKVSC-UHFFFAOYSA-N
56972178

Specifications

Trap 101
1216621-00-9
C24H36ClN3O2
YEVMLMQAMCKVSC-UHFFFAOYSA-N
1-[1-(cyclooctylmethyl)-5-(hydroxymethyl)-3,6-dihydro-2H-pyridin-4-yl]-3-ethylbenzimidazol-2-one;hydrochloride
56972178
50mg
>98%
1-[1-(Cyclooctylmethyl)-1,2,3,6-tetrahydro-5-(hydroxymethyl)-4-pyridinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one hydrochloride
CCN1C2=CC=CC=C2N(C1=O)C3=C(CN(CC3)CC4CCCCCCC4)CO.Cl
434.021
434.02
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