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TRAF-1, clone: 1F3, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9791-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15567686

  • £191.03 / 100µg


Estimated Shipment date
from Supplier 03-04-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The monoclonal antibody 1F3 recognizes human TRAF-1. TRAF-1 is a multifunctional adapter molecule and member of the TNF receptor associated factor protein family. TRAF proteins associate with various receptors of the TNF receptor superfamily to mediate signal transduction. TRAF-1 plays a role in regulating cell survival and apoptosis, regulates the signaling of NF kappa B and JNK, and forms a heterodimeric complex with TRAF-2. TRAF-1 also interacts with cell surface receptors such as CD30, CD40, and CD357 (AITR), and cytoplasmic proteins like NIK, RIP2, A20, and TRIP. Expression of TRAF-1 can be induced by Epstein-Barr Virus (EBV) and TNF alpha.Applications Reported: This 1F3 antibody has been reported for use in western blotting, microscopy, immunohistochemical staining, and immunocytochemistry.Applications Tested: This 1F3 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

TRAF-1
1F3
Unconjugated
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TNF receptor-associated factor 1, EBI6, Epstein-Barr virus-induced protein 6
IgG2a
RUO
Primary
Human
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