TRAF-1 Rat anti-Human, Clone: 1F3, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9791-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15557686

Quantity Price
1 £ 73.93 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Microscopy
Applications Western Blotting
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Isotype IgG2a
Format Purified
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Clone 1F3
Species Reactivity Human
Gene Alias TNF receptor-associated factor 1, EBI6, Epstein-Barr virus-induced protein 6
Quantity 25μg
Concentration 0.5mg/mL
Antigen TRAF-1
Host Species Rat

The monoclonal antibody 1F3 recognizes human TRAF-1. TRAF-1 is a multifunctional adapter molecule and member of the TNF receptor associated factor protein family. TRAF proteins associate with various receptors of the TNF receptor superfamily to mediate signal transduction. TRAF-1 plays a role in regulating cell survival and apoptosis, regulates the signaling of NF kappa B and JNK, and forms a heterodimeric complex with TRAF-2. TRAF-1 also interacts with cell surface receptors such as CD30, CD40, and CD357 (AITR), and cytoplasmic proteins like NIK, RIP2, A20, and TRIP. Expression of TRAF-1 can be induced by Epstein-Barr Virus (EBV) and TNF alpha.