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TRA-1-60 (podocalyxin) Mouse anti-Human, PerCP-eFluor 710, Clone: TRA-1-60, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-8863-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15589376

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Disclaimers:

For Research Use Only.


Description

Description

The TRA-1-60 antibody recognizes a protein expressed on undifferentiated human embryonic stem cells (ES), embyronal carcinoma cells (EC), and embryonic germ cells (EG). Like other stem cell specific markers, the epitope recognized by the TRA-1-60 antibody is lost upon cell differentiation. Contrary to early reports that the TRA-1-60 epitope can be destroyed by neuraminidase digestion, new strudies have shown that TRA-1-60 recognizes a neurominidase resistent antigen. The TRA-1-60 antibody is known to specifically recognize a carbohydrate epitope on a keratan sulfated glycoprotein recently identified as podocalyxin, a member of the CD34-related family of sialomucins. Podocalyxin is a transmembrane glycoprotein originally identified on epithelial glomerular cells known as podocytes, and the protein has also been implicated in the development of aggressiveness in a variety of cancers, including breast and prostate cancer.
Specifications

Specifications

TRA-1-60 (podocalyxin)
TRA-1-60
PerCP-eFluor 710
Conjugated
IgM
RUO
Primary
Human
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal