missing translation for 'onlineSavingsMsg'
Learn More

TQS, Tocris Bioscience™

Positive allosteric modulator of α7 nAChRs

Brand:  Tocris (Bio-Techne) 423350

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

 View more versions of this product

Product Code. 13434404

  • £546.84 / 50mg

Estimated Shipment date
from Supplier 30-03-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Type II positive allosteric modulator of α7 nACh receptors (pEC50 = 5.5). Displays no agonist activity at α7 receptors at concentrations up to 0.1 mM; potentiates agonist-evoked responses and reduces rate of desensitization of α7 nAChRs. Exhibits potency and efficacy similar to PNU 120596 (Cat. No. 2498).
Specifications

Chemical Identifiers

353483-92-8
376.474
tqs, 4-naphthyl-3,4,5,3a,9b-pentahydrocyclopenta 1,2-c quinoline-8-sulfonamide, 3a,4,5,9b-tetrahydro-4-1-naphthalenyl-3h-cyclopentan c quinoline-8-sulfonamide, 4-naphthalen-1-yl-3a,4,5,9b-tetrahydro-3h-cyclopenta c quinoline-8-sulfonamide, 4-naphthalen-1-yl-3h,3ah,4h,5h,9bh-cyclopenta c quinoline-8-sulfonamide
4-naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
C22H20N2O2S
SIZWDJIHABLBSP-UHFFFAOYSA-N
5038679
C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=CC5=CC=CC=C54

Specifications

50mg
353483-92-8
tqs, 4-naphthyl-3,4,5,3a,9b-pentahydrocyclopenta 1,2-c quinoline-8-sulfonamide, 3a,4,5,9b-tetrahydro-4-1-naphthalenyl-3h-cyclopentan c quinoline-8-sulfonamide, 4-naphthalen-1-yl-3a,4,5,9b-tetrahydro-3h-cyclopenta c quinoline-8-sulfonamide, 4-naphthalen-1-yl-3h,3ah,4h,5h,9bh-cyclopenta c quinoline-8-sulfonamide
C1C=CC2C1C(NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=CC5=CC=CC=C54
376.474
376.47
TQS
C22H20N2O2S
SIZWDJIHABLBSP-UHFFFAOYSA-N
4-naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide
5038679
>98%
Videos
Documents