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Torin 1, Tocris Bioscience™

Potent and selective mTOR inhibitor

Brand:  Tocris (Bio-Techne) 424710

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13464424

  • £223.09 / 10mg


Estimated Shipment
02-01-2019
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Description

Description

Potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34. Induces autophagy in HeLa cells.
Specifications

Chemical Identifiers

1222998-36-8
607.637
torin 1, torin1, torin-1, 1-4-4-1-oxopropyl-1-piperazinyl-3-trifluoromethyl phenyl-9-3-quinolinyl benzo h-1,6-naphthyridin-2 1h-one, 1-4-4-propionylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one, 1-4-4-1-oxopropyl-1-piperazinyl-3-trifluoromethyl phenyl-9-3-quinolinyl-benzo h-1,6-naphthyridin-2 1h-one, 1-4-4-propanoylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6-naphthyridin-2-one, 1-4-4-propionylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one, d0h0hr, 1-4-4-propanoylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one
CHEBI:84327
CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F
C35H28F3N5O2
AKCRNFFTGXBONI-UHFFFAOYSA-N
49836027
1-[4-(4-propanoylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-2-one

Specifications

Torin 1
1222998-36-8
torin 1, torin1, torin-1, 1-4-4-1-oxopropyl-1-piperazinyl-3-trifluoromethyl phenyl-9-3-quinolinyl benzo h-1,6-naphthyridin-2 1h-one, 1-4-4-propionylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one, 1-4-4-1-oxopropyl-1-piperazinyl-3-trifluoromethyl phenyl-9-3-quinolinyl-benzo h-1,6-naphthyridin-2 1h-one, 1-4-4-propanoylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6-naphthyridin-2-one, 1-4-4-propionylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one, d0h0hr, 1-4-4-propanoylpiperazin-1-yl-3-trifluoromethyl phenyl-9-quinolin-3-yl benzo h 1,6 naphthyridin-2 1h-one
CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F
607.637
CHEBI:84327
>98%
10mg
C35H28F3N5O2
AKCRNFFTGXBONI-UHFFFAOYSA-N
1-[4-(4-propanoylpiperazin-1-yl)-3-(trifluoromethyl)phenyl]-9-quinolin-3-ylbenzo[h][1,6]naphthyridin-2-one
49836027
607.62
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