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Invitrogen™ TLK1 Recombinant Human Protein

TLK1 or tousled-like kinase 1 is a nuclear serine/threonine kinase that is potentially involved in the regulation of chromatin assembly. Recombinant full-length human TLK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Brand:  Invitrogen™ PV6421

Code : NEW

Additional Details : Weight : 0.01000kg

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Product Code. 15401234

  • £342.00 / 10µg

Estimated Shipment: 12-08-2021

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Description

Description

TLK1 is first described in Arabidopsis. TLK1 is a novel target of the DNA damage checkpoint that is rapidly inactivated upon exposure to ionizing radiation (IR) and the inactivation is directly mediated by the S-phase DNA damage checkpoint. The suppression of TLK1 activity after double-strand breaks in the DNA, replication blockade, or low doses of ultraviolet irradiation requires ATM, NBS and CHK1.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Biochemical binding/kinetic
TLK1
Liquid
Human
113.0 kDa
KIAA0137, PKU-beta
GST Tag
Serine/Threonine Kinase
Baculovirus
Recombinant
Kinase Assay
10μg
Yes
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