TIM4 Rat anti-Mouse, PerCP-eFluor 710, Clone: 54 (RMT4-54), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-5866-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15569286

Quantity Price
1 £ 81.63 / 25µg
Estimated Shipment date
from Supplier 09-05-2017
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Description and Specification

Specification

Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen TIM4
Isotype IgG2a
Format Conjugated
Monoclonal or Polyclonal Monoclonal
Concentration 0.2mg/mL
Clone 54 (RMT4-54)
Conjugate PerCP-eFluor 710
Host Species Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Gene Alias TIMD4, SMUCKLER
Species Reactivity Mouse
Applications Flow Cytometry
Quantity 25μg

The monoclonal antibody 54 (RMT4-54) recognizes mouse Tim-4 (T cell, Ig, mucin). Unlike other Tim family members, Tim-4 is not expressed on T lymphocytes but rather found on antigen presenting cells such as lymphoid and myeloid DC’s and macrophages. Tim-4 has been shown to interact with Tim-1 thereby suggesting a role of Tim-4 in the balance of Th1/Th2 regulation. Additionally Tim-4 has been shown to be a receptor for phosphatidylserine and may play a role in engulfment of apoptotic cells. Expression is found on a subset of CD11c+ splenic cells.