TIM4 Rat anti-Mouse, PE, Clone: 54 (RMT4-54), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-5866-82

Product Code. 15248859

Disclaimers:

For Research Use Only.

Description

The monoclonal antibody 54 recognizes mouse Tim-4 (T cell, Ig, mucin). Unlike other Tim family members, Tim-4 is not expressed on T lymphocytes but rather found on antigen presenting cells such as lymphoid and myeloid DC’s and macrophages. Tim-4 has been shown to interact with Tim-1 thereby suggesting a role of Tim-4 in the balance of Th1/Th2 regulation. Additionally Tim-4 has been shown to be a receptor for phosphatidylserine and may play a role in engulfment of apoptotic cells. Expression is found on a subset of CD11c+ splenic cells.

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Specifications

• Antigen: TIM4
• Clone: 54 (RMT4-54)
• Conjugate: PE
• Formulation: aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
• Host Species: Rat
• Quantity: 100μg
• Storage Requirements: Store at 2-8°C. Do not freeze. Light-sensitive material.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Flow Cytometry
• Concentration: 0.2mg/mL
• Format: Conjugated
• Gene Alias: TIMD4, SMUCKLER
• Isotype: IgG2a
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine