TIM4 Rat anti-Mouse, PE, Clone: 54 (RMT4-54), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5866-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15248859

Quantity Price
1 £ 182.82 / 100µg
EU Stock 2
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Description and Specification

Specification

Gene Alias TIMD4, SMUCKLER
Primary or Secondary Primary
Conjugate PE
Isotype IgG2a
Format Conjugated
Regulatory Status RUO
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Concentration 0.2mg/mL
Applications Flow Cytometry
Antigen TIM4
Quantity 100μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Clone 54 (RMT4-54)
Host Species Rat
Species Reactivity Mouse

The monoclonal antibody 54 recognizes mouse Tim-4 (T cell, Ig, mucin). Unlike other Tim family members, Tim-4 is not expressed on T lymphocytes but rather found on antigen presenting cells such as lymphoid and myeloid DC’s and macrophages. Tim-4 has been shown to interact with Tim-1 thereby suggesting a role of Tim-4 in the balance of Th1/Th2 regulation. Additionally Tim-4 has been shown to be a receptor for phosphatidylserine and may play a role in engulfment of apoptotic cells. Expression is found on a subset of CD11c+ splenic cells.