TIM4 Rat anti-Mouse, PE, Clone: 54 (RMT4-54), eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5866-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15238859

Quantity Price
1 £ 66.65 / 25µg
EU Stock 2
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Description and Specification

Specification

Species Reactivity Mouse
Quantity 25μg
Clone 54 (RMT4-54)
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgG2a
Host Species Rat
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL
Regulatory Status RUO
Primary or Secondary Primary
Format Conjugated
Antigen TIM4
Monoclonal or Polyclonal Monoclonal
Gene Alias TIMD4, SMUCKLER
Applications Flow Cytometry
Conjugate PE

The monoclonal antibody 54 recognizes mouse Tim-4 (T cell, Ig, mucin). Unlike other Tim family members, Tim-4 is not expressed on T lymphocytes but rather found on antigen presenting cells such as lymphoid and myeloid DC’s and macrophages. Tim-4 has been shown to interact with Tim-1 thereby suggesting a role of Tim-4 in the balance of Th1/Th2 regulation. Additionally Tim-4 has been shown to be a receptor for phosphatidylserine and may play a role in engulfment of apoptotic cells. Expression is found on a subset of CD11c+ splenic cells.