TIGIT Rat anti-Mouse, PE, Clone: GIGD7, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9501-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15219359

Quantity Price
1 £ 80.62 / 25µg
EU Stock 2
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Description and Specification

Specification

Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Conjugate PE
Gene Alias VSTM3, WUCAM
Host Species Rat
Isotype IgG2a
Antigen TIGIT
Regulatory Status RUO
Species Reactivity Mouse
Clone GIGD7
Quantity 25μg
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.2mg/mL
Applications Flow Cytometry

The GIGD7 monoclonal antibody reacts with mouse T cell immunoreceptor with Ig and ITIM domains (TIGIT, VSTM3, WUCAM), a 26kDa protein that is a member of the poliovirus receptor (PVR) family. In mice, the expression of TIGIT has been reported in follicular T helper cells, while in humans, the expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells. TIGIT is not expressed on B cells or naïve CD4+ T cells. TIGIT is upregulated on CD4+ T cells following activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK cells and T cells with antigen presenting cells, fibroblasts and endothelial cells that express PVR and PVR-like proteins.