tigit Mouse anti-Human, Clone: MBSA43, Functional Grade, eBioscience™
Mouse Monoclonal Antibody, Functional Grade
Brand: Affymetrix eBioscience 16-9500-85
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionThe MBSA43 monoclonal antibody reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naïve CD4+ T cells. TIGIT may be upregulated on naïve CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins.
MBSA43 is reported to crossreact with Rhesus macaque.
|Store at 2-8°C.|
|aqueous buffer, no sodium azide|