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Thrombospondin-1, clone: A6.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9756-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15567636

  • £70.27 / 25µg


Estimated Shipment date
from Supplier 26-06-2018
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Description

Description

Description: The A6.1 monoclonal antibody recognizes human, mouse, and rat thrombospondin-1, a member of the thrombospondin family of extracellular calcium-binding proteins. Thrombospondin-1 is a secreted glycoprotein that was first discovered in activated platelets but is also expressed by endothelial cells, adipocytes, fibroblasts, macrophages, monocytes, and smooth muscle cells. Thrombospondin-1 functions by binding members of the extracellular matrix such as fibronectin, integrins, and heparin, and its signaling is mediated through activation of the TGF beta signaling pathway. Thrombospondin-1 has been shown to be involved in angiogenesis, inflammation, osteogenesis, cell proliferation, and synaptogenesis during neural development.Applications Reported: This A6.1 antibody has been reported for use in immunoprecipitation, western blotting, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, microscopy, ELISA, and immunocytochemistry.Applications Tested: This A6.1 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using high pH antigen retrieval and can be used at less than or equal to 1 μg/mL. This A6.1 antibody has been tested by immunocytochemistry of formaldehyde or methanol fixed and permeabilized human cells and can be used at less than or equal to 1 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

Thrombospondin-1
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P07996, P35441
THBS, THBS-1, TSP, TSP-1, TSP1, thrombospondin-1, THBS1
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Rat
Western Blot
A6.1
Unconjugated
THBS1
Purified
THBS1
IgG1, kappa
25μg
Store at 2-8°C.
Primary
7057
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