Invitrogen™ Human PRDX6, Recombinant Protein

Recombinant Protein

Brand:  Invitrogen™ LFP0004

Product Code. 10223860

Description

Peroxiredoxin 6 (Hu) Recombinant Protein, LF-P0004, from Invitrogen.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distributionincluding peroxisome, mitochondria and cytosol. This protein corresponds to human Peroxiredoxin VI (1-224 aa), which has a molecular weight of 25 kDa. Purity: >95% by SDS-PAGE.

Specifications

• Accession Number: P30041
• Formulation: 0.02M HEPES with 10% glycerol and no preservative; pH 7.0
• Name: Human PRDX6
• Quantity: 500μg
• Storage Requirements: -20°C
• Common Name: Human PRDX6
• Specific Reactivity: Human
• Cross Reactivity: Hu
• Recombinant: Recombinant
• Protein Subtype: Recombinant

• For Use With (Application): Control
• Gene ID (Entrez): 9588
• pH Range: 7.0
• Source: E. coli
• Regulatory Status: RUO
• Gene Symbol: PRDX6
• Conjugate: Unconjugated
• Species: E. coli
• Form: Liquid
• Purity or Quality Grade: purified

in vitro research only.