Invitrogen™ Human GDF-5 Recombinant Protein

Recombinant Protein

Brand:  Invitrogen™ RP8663

Product Code. 11534970

Description

Growth and Differentiation Factor-5 (human) Recombinant Protein, RP-8663, from Invitrogen.

Growth/Differentiation Factor 5 (GDF-5) is a growth factor that regulates cell proliferation and differentiation in embryonic and adult tissues. GDF-5 is part of the TGF family of proteins and is closely related to the BMP family of proteins. Recombinant human GDF-5 is a non-glycosylated homodimer, containing two 120 amino acids chains, with a total molecular weight of 27.4 kDa. To enable bacterial expression the N-terminal sequence of Ala-Pro-Leu-Thr was replaced with a Lys. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug. The expected biological activity (ED50) is determined by the ability to induce alkaline phosphatase activity in ATDC5 cells is typically 0.1-1 ug/mL. The specific activity of this protein is 1x10^4 units/mg. Reconstitute using sterile water at 0.1mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability. Amino acid sequence: APSATRQGKR PSKNLKARCS RKALHVNFKD MGWDDWIIAP LEYEAFHCEG LCEFPLRSHL EPTNHAVIQT LMNSMDPEST PPTCCVPTRL SPISILFIDS ANNVVYKQYE DMVVESCGCR.

Specifications

• Accession Number: P43026
• For Use With (Application): Control
• Gene ID (Entrez): 8200
• Name: Human GDF5
• Source: E. coli
• Regulatory Status: RUO
• Common Name: Human GDF5
• Specific Reactivity: Human
• Cross Reactivity: Hu
• Recombinant: Recombinant
• Protein Subtype: Recombinant

• Concentration: 0.1mg/mL
• Formulation: 0.1%TFA with no preservative
• Molecular Weight (g/mol): ∽26.8
• Quantity: 50μg
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Gene Alias: H-GDF-5
• Gene Symbol: GDF5
• Conjugate: Unconjugated
• Species: E. coli
• Form: Lyophilized
• Purity or Quality Grade: purified