anti-Bax alpha (human) Recombinant, Thermo Scientific™

Bax alpha (Hu) Recombinant protein RP-800 from Thermo Scientific™ specifically detects Bax alpha (Hu) in Not Applicable samples, and is validated for Control, ELISA, FACS and WB

Brand: Invitrogen

Manufacturer Part Number: RP-800


UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg

Product Code. 11569091

Quantity Price
1 £239.00 / 5µg
Estimated Shipment date
from Supplier 17-11-2016
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Description and Specification


Conjugate Unlabeled
Cross Reactivity Human
For Use With (Application) Control, ELISA, Flow Cytometry, Western Blot
Format Purified
Formulation 5μg purified protein in sodium phosphate, 0.01M tris with 8M urea and no preservative; pH 8.0
Molecular Weight ∽21
Name Human Bax alpha Recombinant Protein
pH Range 8
Quantity 5μg
Recombinant Yes
Source E. coli
Storage Requirements store at -20°C, Avoid Freeze/Thaw Cycles

Members of the Bcl-2 Family (including Bcl-2, Bcl-XLand Bax) play an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, Bax is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of Bax and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa).
Host Species: E. Coli
Formulation: 5μg purified protein in sodium phosphate, 0.01M tris with 8M urea and no preservative; pH 8.0
This human recombinant protein was produced in E. coli. Purity is greater than 95%. RP-800 can be used as a positive control in Western blots, as well as in ELISA and flow cytometry applications. RP-800 calculated molecular weight is ∽21 kDa.