Bax alpha (human) Recombinant Protein, Invitrogen™
Bax alpha (human) Recombinant Protein, RP-800, from Invitrogen™
Brand: Invitrogen RP-800
Code : LD
Additional Details : Weight : 0.01000kg
DescriptionMembers of the Bcl-2 Family (including Bcl-2, Bcl-XLand Bax) play an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, Bax is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of Bax and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa).
Host Species: E. Coli
Formulation: 5μg purified protein in sodium phosphate, 0.01M tris with 8M urea and no preservative; pH 8.0
This human recombinant protein was produced in E. coli. Purity is greater than 95%. RP-800 can be used as a positive control in Western blots, as well as in ELISA and flow cytometry applications. RP-800 calculated molecular weight is ∽21 kDa.
|Control, ELISA, Flow Cytometry, Western Blot|
|5μg purified protein in sodium phosphate, 0.01M tris with 8M urea and no preservative; pH 8.0|
|Human Bax alpha Recombinant Protein|
|store at -20°C, Avoid Freeze/Thaw Cycles|