anti-Bax alpha (human) Recombinant, Thermo Scientific™

Bax alpha (Hu) Recombinant protein RP-800 from Thermo Scientific™ specifically detects Bax alpha (Hu) in Not Applicable samples, and is validated for Control, ELISA, FACS and WB

Overview
Brand: Invitrogen

Manufacturer Part Number: RP-800

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11569091

Quantity Price
1 £ 239.0 / 5µg
Estimated Shipment date
from Supplier 24-05-2017
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Description and Specification

Specification

Formulation 5μg purified protein in sodium phosphate, 0.01M tris with 8M urea and no preservative; pH 8.0
For Use With (Application) Control, ELISA, Flow Cytometry, Western Blot
Host Species E. Coli
Conjugate Unlabeled
Storage Requirements store at -20°C, Avoid Freeze/Thaw Cycles
Cross Reactivity Human
Molecular Weight ∽21
Recombinant Yes
Format Purified
Source E. coli
Quantity 5μg
Name Human Bax alpha Recombinant Protein
pH Range 8

Members of the Bcl-2 Family (including Bcl-2, Bcl-XLand Bax) play an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, Bax is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of Bax and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa).
Host Species: E. Coli
Formulation: 5μg purified protein in sodium phosphate, 0.01M tris with 8M urea and no preservative; pH 8.0
This human recombinant protein was produced in E. coli. Purity is greater than 95%. RP-800 can be used as a positive control in Western blots, as well as in ELISA and flow cytometry applications. RP-800 calculated molecular weight is ∽21 kDa.