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Themis Rat anti-Mouse, PE, Clone: 1TMYS, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-5918-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15507056

  • £78.88 / 25µg


EU Stock 4
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Disclaimers:

For Research Use Only.


Description

Description

This 1TMYS monoclonal antibody reacts with mouse Thymocyte-expressed molecule involved in selection (Themis), also known as Grb2-associating protein (Gasp). Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling.

There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing. The 1TMYS antibody recognizes isoforms 1, 2, 3, and 4, but does not recognize isoform 5.
Specifications

Specifications

Themis
1TMYS
PE
Conjugated
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gasp
IgG2a
RUO
Primary
Murine
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