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Testosterone, Eur.Pharm., Thermo Scientific Chemicals
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Testosterone is a steroid sex hormone from the androstane family and is important for the maintenance of several biological functions
• This compound is an androgen that exerts its function by binding to and activating the androgen receptor
Applications
• Testosterone is irreversibly converted to dihydrotestosterone (DHT) in target tissues by the enzyme 5-∝ reductase
• Testosterone or DHT (its active metabolite) ligand-androgen receptor complexes act as a transcription factor, stimulating the expression of several responsive genes
• It antagonizes the androgen receptor to induce gene expression that causes the growth, development, and maintenance of several biological functions
• This compound is commonly used in vivo studies as an ester derivative due to its rapid metabolism by the liver
Specifications
Melting Point | 153.0°C to 157.0°C |
Packaging | Glass bottle |
Quantity | 5 g |
Merck Index | 15, 9324 |
Specific Rotation | +110.00 |
Solubility Information | Solubility aq. soln.: insoluble. Other solubilities: soluble in chloroform, alcohol, acetone, benzene,, dioxane and vegetable oils, slightly soluble in ether |
Formula Weight | 288.42 |
Chemical Name or Material | Testosterone |
Safety and Handling
- Testosterone
- Danger
- Acute toxicity Category 4
- ACUTE AQUATIC Acute 1
- Carcinogenicity Category 2
- Reproductive toxicity on or via lactation
- Reproductive toxicity Category 1A
- H400-Very toxic to aquatic life.
- H360FD-May damage fertility. May damage the unborn child.
- H351-Suspected of causing cancer.
- H362-May cause harm to breast-fed children.
- H302-Harmful if swallowed.
- P260-Do not breathe dust/fume/gas/mist/vapours/spray.
- P273-Avoid release to the environment.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
- P330-Rinse mouth.
RUO – Research Use Only