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TdT Mouse, Clone: 7UNA8U6, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9739-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15547616

  • £61.70 / 25µg


Estimated Shipment date
from Supplier 31-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody 7UNA8U6 reacts with human, mouse, and rat TdT. TdT, or terminal-deoxynucleotidyl transferase, is a 60kDa polymerase responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. Expression is found in the nucleus of immature lymphocytes but not in mature lymphocytes or non-lymphoid cells. TdT plays a critical role during TCR and Ig gene rearrangement and functions to increase the diversity of the lymphocyte repertoire through the addition of N-nucleotides onto the ends of newly formed P-nucleotides. After positive selection, expression of TdT becomes decreased or absent. Expression of TdT has been shown to be present in lymphoma or lymphoblastic leukemia cells.
Description & Specifications

Specifications

TdT
7UNA8U6
Unlabeled
Purified
Murine
25μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Terminal-deoxynucleotidyl transferase
IgG1
RUO
Primary
Rat